Custom Curation

Molecular Connections' Expert Curation & Analysis Services

Expert Curation & Analysis Services are scientific services that can help expedite your research programs. The key value proposition is to leverage the ability to interpret analyze your organization's research/experimental data and correlate it with our vast Knowledge Platforms unearthing new connections to be found and novel hypotheses to be generated.

The data is made seamlessly available across our knowledge platforms breaking down the scientific silos that often exist within organizations. Our services leverage the knowledge of skilled professionals and best practices, and are tailored to meet your specific business needs. Our team of experts can help with:

• Analysis and interpretation of 'Systems Biology'/ 'ome & omic' datasets for compound profiling, lead identification and prioritization of therapeutic targets, and understanding disease mechanism of action and mechanism of toxicity. All interpretations validated by evidences from scientific literature.
  
• Our data analysis specialists will aggregate relevant raw data sets, monitor the analysis workflow systems, and Transform your raw data into analysis results Building biological models of disease processes for target identification and validation research
  
• Identification and prioritization of biomarkers via analysis of gene expression, proteomics, and data from literature and open source databases
  
• Delivering a focused toxicity and target reports of your drug candidates
  
• Creating clear report summaries and graphics or pathways for better understanding and expedite decision making

Expert Curation & Analysis Services leverage our Proprietary workflow systems for target curation. Extremely modular and an end-to-end platforms for literature mining and creating target based databases. An intuitive, innovative and rigorous analysis workflow system, which consists of comprehensive quality control steps as well as the semi-automated review and tagging of the results by our expert scientific team, can translate large volumes of experimental data into research-ready content.

Optimize the flow of research information across your enterprise, enabling faster access to the mission-critical scientific information that runs your research and development organization.

Data Assessment and Aggregation Our expert analyst team will assist your onsite teams to identify and evaluate your current and legacy data.

Custom Curation & Analysis Our highly expert scientific team will analyze your data and process it through our proven analysis workflow systems. Your raw data will be carefully analyzed and put through a rigorous QC process resulting in High Quality Knowledge thus delivered wrapped with in intuitive and analytical software allows researchers more time for science and eliminates the need to consult BioIT experts.

Data Tagging Our scientific team will annotate all the data produced by the analysis workflow systems with relevant ontology terms based on standard disease, tissue and drug vocabularies, as well as relevant experimental methods & designs. The tagging process adds semantic structure to your data, allowing it to be more easily accessed and utilized across your research infrastructure.

Custom Interactions & Networks: Both static and dynamic maps with underlying meta-data validated by embedded compendiums. The compendium provide complete annotation and references from literature and public databases along with expert curation and annotation by our Scientists

• Insights to understand key genes or processes in a system of interest.
  
• Validate experimental assumptions
  
• Biological context & significance of genes
  
• Relationships between interacting biological entities (genes, small molecules, RNA, DNA, ect.)
  

Content Enrichment & Knowledge Management: Application of rational approach to workflow automation to increase time for science. Analytical application development over existing search framework to enable analysis and refining of the content presented from the search. Organize complex Experimental data using specialized dictionaries, thesaurus and glossaries.

Molecular Connections' Expert Curation & Analysis Services provide the strategic guidance and scientific expertise life science organizations need to address their information challenges and gain maximum value from their research information assets. We strive to assist your organization in harnessing your information to extract maximum value from all types of biological and chemical knowledge.

• Largest manually curated interaction database covering proteins and small molecules
• Extensive coverage of protein classes ranging from LRPs to secondary messengers and siganalling molecules to transcription regulators.
• Usage of standards like controlled vocabularies compliant to public domains like MeSH, NCBI, GO etc and data validations Data available in standard and customized formats for easy integration with in-house / external databases
• Novel compound library with structures and SAR, QSAR data.
• Wide range of species covered- human, mouse, rat, other mammals and non-mammals, virus, bacteria etc. Records supported by references
• Expert Curated information on 'disease - gene' (mutation, expression, targeting, biological marker), 'disease - compound' (therapeutic relevance, efficacy), 'disease - interaction' (variation)