| Interaction ID | Mol A | Type | Species | Verb | Nature | Mol B | Type | Species |   |
|---|
|
| 75573 | Troglitazone | Small molecule | Small molecule | Increases activity | direct | PPARG | Protein | Homo sapiens-e | | | The PPARgamma agonists 15dPGJ(2),
trogliltazone (TGZ), and GW7845, a synthetic and highly
selective tyrosine-based PPARgamma agonist, all increased
transcriptional activity of PPARgamma, and expression of
CD36, a PPARgamma-dependent gene. | | | |
Interaction id | 75573 | |
MOLECULE A | |
Id | 97322-87-7 |
Type | Small molecule |
Species | Small molecule | |
Attribute |
--
|
Structure Details | -- |
Disease Details | -- | |
MOLECULE B | |
Id | 5468 |
Type | Protein |
Species | Homo sapiens-e | |
Attribute | -- |
Structure Details | -- |
Disease Details | -- | | Kinetics | - | |
|
General Information |
Interaction term | Increases activity (
direct ) | |
Pathway | Ligand-dependent nuclear receptor
activity:Peroxisome proliferator associated receptor activity | |
References | |
PubMed Id | 12401880 | |
Author | Clay CE, Monjazeb A, Thorburn J, Chilton FH, High KP | |
Title | 15-Deoxy-delta12,14-prostaglandin J2-induced apoptosis does
not require PPARgamma in breast cancer cells. |
|
|
| |
|
d: for diseases
