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The RXR ligand, 9-cis retinoic acid (9cRA),
reduced TNF-alpha mRNA abundance in BMMs, but increased CD14
mRNA levels. 9cRA decreases TNF-alpha mRNA by destabilizing
the transcript, and possibly also by forming
transcriptionally inactive complex with 1 ,25(OH)(2)D(3) on
the tnfVDRE.