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Interaction IDMol ATypeSpeciesVerbNatureMol BTypeSpecies
33672AlitretinoinSmall moleculeSmall moleculeDecreases expressionindirectTNFRNAHomo sapiens-e
The RXR ligand, 9-cis retinoic acid (9cRA), reduced TNF-alpha mRNA abundance in BMMs, but increased CD14 mRNA levels. 9cRA decreases TNF-alpha mRNA by destabilizing the transcript, and possibly also by forming transcriptionally inactive complex with 1 ,25(OH)(2)D(3) on the tnfVDRE.
Regulator