|
Interaction id | 191595 |
|
MOLECULE A |
|
Id | 3553 |
Type | Protein |
Species | Homo sapiens-e |
|
Attribute |
--
|
Structure Details | -- |
Disease Details | -- |
|
MOLECULE B |
|
Id | 25493 |
Type | Protein |
Species | Rattus norvegicus |
|
Attribute | -- |
Structure Details | -- |
Disease Details | -- |
| Kinetics | | Mol B | | Conc | Time | Others | Comments | | after5min
| | Detectable / apparent
|
|
| Mol B | | Conc | Time | Others | Comments | | after15min
| | Complete degradation
|
|
| Mol B | | Conc | Time | Others | Comments | | after45 to 60min
| | Returned to basal level
|
|
|
|
|
General Information |
Interaction term | Increases degradation (
indirect ) | |
Pathway | Cytokine And Chemokine Mediated Signaling
Pathway:IL1 Signaling Pathway |
|
Experimental location and method | - species::Rat
- cell::C6 cells
|
|
References |
|
PubMed Id | 10336492 |
|
Author | Uehara T, Matsuno J, Kaneko M, Nishiya T, Fujimuro M,
Yokosawa H, Nomura Y |
|
Title | Transient nuclear factor kappaB (NF-kappaB) activation
stimulated by interleukin-1beta may be partly dependent on
proteasome activity, but not phosphorylation and ubiquitination
of the IkappaBalpha molecule, in C6 glioma cells. Regulation of
NF-kappaB linked to chemokine production. |
d: for diseases
