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The results demonstrate that LPS, IL-1beta,
and TNF-alpha induce p100 expression at mRNA and protein
level while IFN-gamma, IL-3 and IL-4/IL-10 have no
effect.The induction of p100 expression was shown to be
mediated by a two-fold increase in the p100 transcription
rate and a two-fold increase in p100 mRNA stability.